Hirschsprung Disease

Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.

Also Known As:

Hirschsprung's Disease; Congenital Megacolon; Aganglionic Megacolon; Aganglionosis, Rectosigmoid Colon; Aganglionosis, Total Colonic; Congenital Intestinal Aganglionosis; Megacolon, Aganglionic; Rectosigmoid Aganglionosis; Total Colonic Aganglionosis; Aganglionosis, Rectosigmoid; Disease, Hirschsprung; Disease, Hirschsprung's; Hirschsprungs Disease; Rectosigmoid Colon Aganglionosis; Aganglionosis, Colonic; Colonic Aganglionosis; Megacolon, Congenital

Digestive System Diseases: 1042
- Gastrointestinal Diseases: 5874
  - Intestinal Diseases: 1601
    - Colonic Diseases: 359
      - Megacolon: 321
        Hirschsprung Disease: 1458
- Digestive System Abnormalities
  - Hirschsprung Disease: 1458
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Congenital Abnormalities: 25723
  - Digestive System Abnormalities
    - Hirschsprung Disease: 1458

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Disease

Drug/Important Bio-Agent (IBA)